Toxicology

Synonyms:  U AMPH SCRN; speed
Profile/Panel Components: Amphetamines testing is included in a UDS12 along with barbiturates; benzodiazepines; cocaine; opiates; methadone; PCP; methamphetamine; propoxyphene; THC; MDMA; oxycodone; osmolality.  Confirmation for a positive AMPHETAMINES URINE SCREEN must be confirmed by ordering AMPHETAMINES URINE CONFIRMATION, MML 8257.
Patient Preparation: None

SPECIMEN COLLECTION
Specimen Type: Random urine
Collection Requirement: Collect specimen in a clean container without preservative.
Minimum Volume:  1.0 mL
Cause for Rejection:  Unlabeled or QNS samples will be rejected.
Specimen Handling/Stability: Specimen stable for 8 hours at room temperature.
Specimen Storage Stability: Samples are maintained and saved in the laboratory for 7 days at 4 ^OC. Specimens that test positive are saved for one month at ?20 ^OC.

TEST AVAILABILITY:  24 hours daily

TURN AROUND TIME:  Routine: 4 Hours STAT: 45 minutes

REFERENCE RANGE:  Negative

SPECIAL INSTRUCTIONS:  Specimens that test positive are saved for one month at ?20 ^OC.

Revised 9/7/2010 CC 

Synonyms: U BARB SCRN
Profile/Panel Components:  Barbiturates testing is included in a UDS12 along with amphetamines; benzodiazepines; cocaine; opiates; methadone; PCP; methamphetamine; propoxyphene; THC; MDMA; oxycodone; osmolality. 
Patient Preparation: None

SPECIMEN COLLECTION
Specimen Type: Random urine
Collection Requirement: Collect specimen in a clean container without preservative.
Minimum Volume:  1.0 mL
Cause for Rejection:  Unlabeled or QNS samples will be rejected.
Specimen Handling/Stability: Specimen stable for 8 hours at room temperature.
Specimen Storage Stability: Samples are maintained and saved in the laboratory for 7 days at 4 ^OC. Specimens that test positive are saved for one month at ?20 ^OC.

TEST AVAILABILITY:  24 hours daily

TURN AROUND TIME:  Routine: 4 Hours STAT: 45 minutes

REFERENCE RANGE:  Negative 

SPECIAL INSTRUCTIONS:  Specimens that test positive are saved for one month at ?20 ^OC.

Revised 9/7/2010 CC

TEST NAME:  DRUG MECONIUM, Stool

Synonyms:  New born drug screen
Panel/Profile Components:  Drugs tested for amphetamines, cannabinoids, cocaine and metabolites and opiates
Patient Preparation:  None

SPECIMEN COLLECTION
Specimen Type:  stool/feces
Drawing Requirements:  Infants first bowl movement should be collected by nursery.  AIT specimen chain of custody (COC) should be completed by collecting nurse.  Send specimen at room temperature to AIT Laboratories for testing.   
Minimum Volume:  No minimum volume.
Cause for Rejection:  Unlabeled specimen or missed first bowl movement
Specimen Handling/Stability: Specimen stable for shipment at room temperature but refrigerate specimen upon arrival in the laboratory if it is not packaged for shipment immediately.
Specimen Storage Stability:  Samples are sent to AIT Laboratories for testing.

TEST AVAILABILITY:  Reference laboratory testing performed by AIT Laboratories.

TURN AROUND TIME:5-10 days

REFERENCE RANGE:     Amphetamines:  Negative
                                      Cannabinoids:  Negative
                                      Cocaine Metabolites:  Negative
                                      Opiates:  Negative

SPECIAL INSTRUCTIONS:  Send specimen and completed chain of custody (COC) via UPS to AIT Laboratories for testing. 

Revised 5/19/2010 CC

 TEST NAME:  U ECSTASY (MDMA) SCREEN, Urine
Refer to U MDMA SCREEN, Urine

Revised 9/7/2010 CC

TEST NAME:  ETHANOL BREATH SCREEN, Breath
Call the laboratory for specific instructions from testing personnel.

Revised 5/22/2010 CC

TEST NAME: ETHANOL, Plasma

SPECIMEN COLLECTION
Specimen Type:   Plasma
Drawing Requirements:  DO NOT USE AN ALCOHOL PAD TO CLEANSE THE SKIN PRIOR TO SPECIMEN COLLECTION.  Draw blood in a gray top sodium fluoride tube.
Minimum Volume:  0.5 mL plasma
Cause for Rejection: Unlabeled specimen, QNS, specimen drawn in wrong tube, not drawn under chain of custody.         Specimen must be collected with chain of custody and no alcohol pad used to cleanse skin.  A chain of custody can be obtained from the laboratory.  No ethanol testing will be performed with out a properly completed chain of custody. 
Specimen Handling/Stability: Specimen stable for 8 hours at room temperature.
Specimen Storage Stability: Samples are maintained and saved in the laboratory for 6 months at -20 ^OC.

TEST AVAILABILITY:  7 Days/24 Hours

TURN AROUND TIME:  STAT: 45 Minutes Routine: 2 Hours

REFERENCE RANGES:       Legal Intoxication          Critical Level               LD50 
                                          >80 mg/dL (0.080%)          >300 mg/dL           >400 mg/dL

SPECIAL INSTRUCTIONS: Specimen must be always be collected under Chain of Custody. 

Revised 5/22/2010 CC

TEST NAME: ETHANOL, Whole Blood
MML # 8264

Synonyms: alcohol, ethyl alcohol, blood alcohol, ETOH
Panel/Profile Component:  None
Patient Preparation:  None

SPECIMEN COLLECTION:
Specimen Type:  Whole blood
Drawing Requirements:  Draw blood in a grey-top (potassium oxalate/sodium fluoride) tube and send 2 mL of potassium oxalate/sodium fluoride whole blood.  Specimen must be sent in original vacutainer at ambient temperature but refrigerated or frozen specimen will also be accepted.  For situations were chain-of-custody (COC) is required, call the laboratory for a Mayo Medical Laboratories Chain-of-Custody kit.   
Minimum Volume: 0.5 mL
Cause for Rejection: Unlabeled, QNS specimen or samples drawn in wrong tube and/or without proper COC (where required) will be rejected.
Specimen Handling/Stability: Specimen stable for 8 hours at room temperature.
Specimen Storage Stability: Specimen stable for 7 days at -20 ^OC.  Sample is sent to Mayo Medical Laboratories for testing. 

TEST AVAILABILITY:  Reference laboratory testing performed by Mayo Medical Laboratories Monday-Sunday at various times.

TURN AROUND TIME: 1-2 days

REFERENCE RANGES:      Not detected (positive results are quantified)
Limit of detection:  10 mg/dL (0.01 g/dL)
Legal limit of intoxication is 80 mg/dL (0.08 g/dL)
Toxic concentration is dependent upon individual usage history
Potentially lethal concentration:  >/= 400 mg/dL (0.4 g/dL)

SPECIAL INSTRUCTIONS:  Specimen must be sent in original vacutainer at ambient temperature but refrigerated or frozen specimen will also be accepted.  For situations were chain-of-custody (COC) is required, call the laboratory for a Mayo Medical Laboratories Chain-of-Custody kit. 

 TEST NAME:  U MDMA (Ecstasy) SCREEN, Urine

Synonyms: U MDMA SCRN, ecstasy
Profile/Panel Components:  Ecastsy (MDMA)testing is included in a UDS12 along with amphetamines; barbiturates; benzodiazepines; cocaine; opiates; methadone; PCP; methamphetamine; propoxyphene; THC; oxycodone; osmolality. 
Patient Preparation: None

SPECIMEN COLLECTION
Specimen Type: Random urine
Collection Requirement: Collect specimen in a clean container without preservative.
Minimum Volume:  1.0 mL
Cause for Rejection:  Unlabeled or QNS samples will be rejected.
Specimen Handling/Stability: Specimen stable for 8 hours at room temperature.
Specimen Storage Stability: Samples are maintained and saved in the laboratory for 7 days at 4 ^OC. Specimens that test positive are saved for one month at ?20 ^OC.

TEST AVAILABILITY:  24 hours daily

TURN AROUND TIME:  Routine: 4 Hours STAT: 45 minutes

REFERENCE RANGE:  Negative 

SPECIAL INSTRUCTIONS:  Specimens that test positive are saved for one month at ?20 ^OC.

Revised 9/7/2010 CC

 TEST NAME:  U METHADONE SCREEN, Urine

TEST NAME: METHADONE CONFIRMATION, Urine
MML # 83129

Synonyms: Dolopine
Panel/Profile Component:  None
Patient Preparation: None

SPECIMEN COLLECTION
Specimen Type: Random urine
Collection Requirement:  Collect 20 mL random urine with no preservatives.  Immediately refrigerate the sample and send it in a screw top plastic 60 mL urine container.  For situations where a chain of custody (COC) is required, kits are available.
Minimum Volume: 2.5 mL
Cause for Rejection:   Unlabeled, QNS specimen or samples drawn in wrong tube and/or without proper COC (where required) will be rejected.
Specimen Handling/Stability: Refrigerate sample promptly and maintain the chain of custody carefully if required.
Specimen Storage Stability: Sample is sent to Mayo Medical Laboratories for testing.
 
TEST AVAILABILITY:  Reference laboratory testing performed by Mayo Medical Laboratories Monday, Thursday and Saturday with no results reported on Sunday.

TURN AROUND TIME:  2-5 days

 TEST NAME:  U METHAMPHETAMINE SCREEN, Urine

TEST NAME: OPIATES, Urine
MML # 8473

Synonyms:  codeine; dilaudid; heroine (as morphine); hycodan; vicodin; hydrocodone; lortab; opiate; oxycontin; percodan
Panel/Profile Component:  To insure the integrity of the sample, an adulterant survey is always performed.
Patient Preparation:  None

SPECIMEN COLLECTION
Specimen Type:  Urine
Drawing Requirements:  20 mL random urine, with no preservatives, refrigerated in a skew top plastic urine transport container.  Laboratory reference department must be consulted prior to specimen collection if a chain of custody (COC) is required or is in question.
Minimum Volume: 2.5 mL
Cause for Rejection:  Samples that are not labeled or QNS will be rejected.  Testing will not be performed on samples that are positive for adulterants.
Specimen Handling/Stability: Refrigerated sample promptly.
Specimen Storage Stability: Specimen is sent to Mayo Medical Laboratories for testing.

TEST AVAILABILITY: Reference laboratory testing performed by Mayo Medical Laboratories Monday-Friday.

TURN AROUND TIME:2-5 days

REFERENCE RANGE:Negative
Positives reported with a quantitative GC/MS result
Cuttoff concentrations are as follows:
Immunoassay screen:
     <300 ng/dL
Codeine by GC/MS
     <100 ng/mL
Hydrocodone by GC/MS
     <100 ng/mL
Hydromorphone by GC/MS
     <100 ng/mL
Oxycodone by GC/MS
     <100 ng/mL
Morphine by GC/MS
     <100 ng/mL

SPECIAL INSTRUCTIONS:  Reid Hospital Laboratory reference department must be consulted prior to specimen collection if a chain of custody (COC) is required or is in question.

Revised 6/16/2010 CC